Mohammadtaghi Shakeri; Mohammad Sadegh Marvi; Hamidreza SafaBakhsh; Parastoo Jamili; Reyhaneh Bazargani
Volume 20, Issue 4 , January and February 2014, , Pages 464-471
Abstract
Background: Human T-lymphotropic virus (HTLV), a retrovirus, is the causative agent of adult T-lymphocytic leukemia (ATL) and tropical spastic paraparesia (TSP). HTLV-1 is transmitted mainly through blood transfusion. Sabzevar is an endemic region for HTLV infection; hence it is essential to detect the ...
Read More
Background: Human T-lymphotropic virus (HTLV), a retrovirus, is the causative agent of adult T-lymphocytic leukemia (ATL) and tropical spastic paraparesia (TSP). HTLV-1 is transmitted mainly through blood transfusion. Sabzevar is an endemic region for HTLV infection; hence it is essential to detect the prevalence of HTLV1/2 infection in the blood donors of this city.
Materials and Methods: In this cross-sectional study, blood samples of all donors referring to Sabzevar Blood Transfusion Center from 2007 to 2008 were screened for HTLV infection using ELISA, and positive samples were confirmed by western blotting. Data were analyzed in SPSS software version 17.0 using Chi squared and Student's t-test.
Results: The results showed that 56 of donors (44 male: 78.6% and 12 female: 21.4%) were infected to HTLV, with average age 40.27±10.02. The prevalence of HTLV infection among all donors was 0.26%. There was a significant correlation between age, marital status, times of blood donation and educational levels and HTLV infection.
Conclusions: Regarding lower rate of infection among younger and regular blood donors and donors with higher educational levels, it should be considered to select donors from this population.
MR HAMEDI NIA; AH HAGHIGHI; P JAMILI
Volume 13, Issue 4 , January and February 2007, , Pages 204-210
Abstract
Background and purpose: C-reactive protein is a sensitive, nonspecific marker of inflammation and its relationship with coronary vascular disease is already established. The present research was conducted to study the effect of resistance training on the rate of C-reactive protein in obese men.
Methods ...
Read More
Background and purpose: C-reactive protein is a sensitive, nonspecific marker of inflammation and its relationship with coronary vascular disease is already established. The present research was conducted to study the effect of resistance training on the rate of C-reactive protein in obese men.
Methods and Materials: The present study was quasi-experimental and 24 male subjects (16 obese, 8 lean) with age range of 35 to 48 years voluntarily participated in the study. Obese men were randomly assigned into two groups: resistance training and control group. The third group included the lean men subjects. Fasting blood samples were taken from all subjects. The experimental subjects received resistance training for 13 weeks, 3 sessions per week. The resistance training was done in circuit fashion in 11 stations with a 50 to 60% intensity of one maximum repetition (IRM).
Results: Resistance training significantly decreased the serum CRP levels of the obese men (from 1.65±0.6 to 0.53±0.73). In addition, serum CRP concentrations in obese men at baseline state were significantly higher than those in lean men (1.56±0.58 versus 0.26±0.21). In all subjects there was a significant and positive correlation between serum CRP levels and obesity markers (r=0.75) and different components of the metabolic syndrome.
Conclusion: Resistance training due to antinflammatory effects is likely to reduce the risk of future cardiovascular events in obese men.